MRI Contrast Agents and Nephrogenic Systemic Fibrosis (NSF). The American College of Radiology (ACR) Contrast Committee and the Subcommittee for MR Safety members recommend pre-screening patients prior to the administration of Gadolinium-Based MR Contrast Agents (GBMCA), as follows:

A recent (e.g., last 6 weeks) Glomerular Filtration Rate (GFR) assessment be reviewed for patients with a history of:

  • Renal disease (including solitary kidney, renal transplant, renal tumor)
  • Age >60 years old -History of Hypertension -History of Diabetes
  • History of severe hepatic disease/liver transplant/pending liver transplant.

For patients in this category, only, it is recommended that the patient’s GFR assessment be nearly contemporaneous with the MR examination for which the GBMCA is to be administered.